Hyun Min Jung, Ph.D.

Hyun-Min Jung, M.S.hjung@dental.ufl.edu | Curriculum Vitae

Hyun Min earned his B.S. in Biological Sciences from Ajou University, Suwon, South Korea, and M.S. in Molecular Genetics from CHA University, Seongnam, South Korea. After doing research in cancer biology during his Master’s training, he entered the Interdisciplinary Program in Biomedical Sciences (IDP) at the University of Florida in 2009 and joined the Chan Laboratory in 2010. His doctoral dissertation focused on the molecular mechanisms underlying oral cancers, specifically related to miRNA-mediated post-transcriptional regulation of oncogenes or tumor suppressor genes.

Education

  • Ph.D. in Biomedical Science, University of Florida, 2009-2013
  • M.S. in Molecular Genetics, CHA University, Seongnam, South Korea, 2006-2008
  • B.S. in Biological Sciences, Ajou University, Suwon, South Korea, 1999-2006

Research Experience

  • 2010-present: Graduate Research Assistant, University of Florida. Laboratory of Edward K.L. Chan, Ph.D. Project: miR-375 regulates Wnt/Β-catenin signaling and telomerase activity in oral cancers.
  • 2008-2009: Lab Researcher, CHA University. Laboratory of Jin-Kyeoung Kim, Ph.D. Project: miRNA expression in tissues from human lung tumor patients and blood samples of stroke patients.
  • 2006-2008: Graduate Research Assistant, CHA University. Laboratory of Jin-Kyeoung Kim, Ph.D. Project: Expression profiling of genes in SV40-immortalized cells and identification of novel genes.
  • 2005-2006: Undergraduate Research Assistant, Ajou University. Laboratory of Eun-Pyo Moon, Ph.D. Project: Study of glycinecin A resistant activity acquired by transposon Tn5.
  • 2000-2001: Undergraduate Research Assistant, Ajou University. Laboratory of Hong-Keun Choi, Ph.D. Project: Genetic variation of sex determination among the Gingko species in Korea.

Teaching Experience

  • 2013-present: Teaching Assistant, GMS5905: RNA Interference and microRNAs: From Advances in Cell Biology to Therapeutic Applications in the Treatment of Human Diseases
  • 2004-2005: Camp Counselor, Pharos English Camp, South Korea
  • 2003-2004: Science Instructor, Dae-gwang Academic Institute, South Korea
  • 2001-2003: Drill Assistant, Korean Military Recruit Training Center, South Korea

Training Experience

  • 2013-present: Mentoring undergraduate student Yoel Benarroch (UF Microbiology)
  • 2013-present: Training a visiting scholar Tatiana Liborio, DDS, PhD, Federal University of Amazonas, Brazil
  • 2012-2013: Mentoring undergraduate student Brittany L. Phillips (UF Microbiology & Cell Science), currently a graduate student at Emory University
  • 2008-2009: Mentoring undergraduate student Sung-Hwan Hong (CHA University)

Publications

Jung, H.M., Phillips, B.L., and Chan, E.K.L. (2013) Simultaneous modulation of p53-p21 network and telomerase activity by miRNA-mediated human papillomavirus type 16 post-transcriptional regulation. Manuscript in preparation.

Jung, H.M., Patel, R.S., Phillips, B.L., Wang, H., Cohen, D.M., Reinhold, W.C., Chang, L.J., Yang, L.J., and Chan, E.K. Tumor suppressor miR-375 regulates MYC expression via repression of CIP2A coding sequence through multiple miRNA-mRNA interaction. Mol Biol Cell. 24:1638-48.

Jung, H.M., Phillips, B.L., Patel, R.S., Cohen, D.M., Jakymiw, A., Kong, W.W., Cheng, J.Q., and Chan, E.K.L. (2012) Keratinization-associated miR-7 and miR-21 regulate tumor suppressor reversion-inducing-cysteine-rich protein with kazal motifs (RECK) in oral cancer. J. Biol. Chem. 287(35):29261-72.

Yao, B., Li, S., Jung, H.M., Lian, S.L., Abadal, G.X., Han, F., Fritzler, M.J., and Chan, E.K.L. (2011) Divergent GW182 functional domains in the regulation of translational silencing. Nucleic Acids Res. 39(7):2534-2547.

Jeon, S.Y., Lee, H.J., Park, J.M., Jung, H.M., Yoo, J.K., Lee, H.J., Lee, J.S., Cha, D.H., Kim, J.K., and Kim, G.J. (2010) Increased immortalization-upregulated protein 2 (IMUP-2) by hypoxia induces apoptosis of the trophoblast and pre-eclampsia. J. Cell. Biochem. 110(2):522-530.

Jung, H.M., and Kim, J.K. (2010) Identification and characterization of WSG, a fusion gene associated with the proliferation of the WI-38 VA13 cells. Exp. Lung Res. 36(3): 140-147.

Jung, H.M., Choi, S.J., and Kim, J.K. (2009) Expression profiles of SV40-immortalization-associated genes upregulated in various human cancers. J. Cell. Biochem. 106(4):703-713.

Ahn, J.S., Moon, S.H., Yoo, J.K., Jung, H.M., Chung, H.M., and Kim, J.K. (2008) Expression of the C1orf31 gene in human embryonic stem cells and cancer cells. Reproductive and Developmental Biology 34(4): 233-237.

Jung, H.M., Choi, S.J., Kim, S.H., Moon, S.H., Yoo, J.K., Chung, H.M., and Kim, J.K. (2008) Expression of HERV-HX2 in cancer cells and human embryonic stem cells. Reproductive and Developmental Biology 32(2):105-110.

Kim, S.J., An, H.J., Kim, H.J., Jung, H.M., Lee, S., Ko, J.J., Sakuragi, N., and Kim, J.K. (2007) IMUP-1 and IMUP-2 overexpression in endometrial carcinoma in Korean and Japanese populations. Anticancer Res. 28(2A):865-871.

Choi, H.J., Kim, G.I., Kim, H.J., Jung, H.M., Noh, H.M., Kim, K.S., and Kim J.K. (2006) Discovery of differentially overexpressed genes in immortalized cells and human pulmonary non-small cell carcinomas. J Lung Cancer. 5(2):96-101.

International Conference Presentations

Jung, H.M., Patel, R.S., Cohen, D.M., Jakymiw, A., Kong, W.W., Cheng, J.Q., and Chan, E.K.L. (2012) Sub-classification of oral cancers using a miRNA-based combinatorial approach. American Association for Cancer Research, Chicago, IL, USA. Poster presentation.

Jung, H.M., Patel, R.S., Cheng, J.Q., and Chan, E.K.L. (2011) Downregulated miR-375 in tongue cancer and its putative role as a tumor suppressor microRNA. American Association for Cancer Research, Orlando, FL, USA. Poster presentation.

Jung, H.M., Patel, R.S., Cheng, J.Q., and Chan, E.K.L. (2011) Identification of miR-375 as a tumor suppressor microRNA in human tongue cancers. Keystone Symposia on Molecular and Cellular Biology, Monterey, CA, USA. Poster presentation.

Jung, H.M., Hong, S.W., and Kim, J.K. (2008) Characterization of immortal-up-regulated & senescent-down-regulated novel genes discovered from immortalized cell. The 65th Korean Society for Biochemistry and Molecular Biology, Seoul, South Korea. Poster presentation.

Jung, H.M. and Kim, J.K. (2008) Cloning and analysis of novel genes discovered from immortalized cell by suppression subtractive hybridization. Keystone Symposia on Molecular and Cellular Biology, Vancouver, Canada. Poster presentation.

Jung, H.M., Kwon, Y.D., Ko, J.J, and Kim, J.K. (2007) Novel genes discovered by SSH may play a role of cell immortalization of proliferation. The 30th Annual Meeting of Molecular Biology Society of Japan, Yokohama, Japan. Poster presentation.

Jung, H.M., Choi, H.J., Kim, H.J., Noh, H.M., Ko, J.J., and Kim, J.K. (2006) Detection of genes from WI-38 VA-13 that are presumed to regulate the immortalization of cell. The 29th Annual Meeting of Molecular Biology Society of Japan, Kyoto, Japan. Poster presentation.

Local Meeting Presentations

Jung, H.M., Patel, R.S., Phillips, B.L., Cohen, D.M., and Chan, E.K.L. (2012)  miR-375 regulation of CIP2A controls oral cancer cell proliferation and survival. UF Graduate Student Research Day, Gainesville, FL, USA. Poster presentation.

Jung, H.M., Patel, R.S., Cohen, D.M., Jakymiw, A., Kong, W.W., Cheng, J.Q., and Chan, E.K.L. (2012) Keratinization-associated miR-7 and miR-21 regulate tumor suppressor RECK in oral cancer. UF&Shands Cancer Center Research, Gainesville, FL, USA. Poster presentation.

Jung, H.M., Patel, R.S., Cohen, D.M., Jakymiw, A., Kong, W.W., Cheng, J.Q., and Chan, E.K.L. (2012) Keratinization-associated miR-7 and miR-21 regulate tumor suppressor RECK in oral cancer. UF College of Dentistry Spring Synergy – Celebration of Science, Gainesville, FL, USA. Oral presentation.

Jung, H.M., Patel, R.S., Cohen, D.M., Jakymiw, A., Cheng, J.Q., and Chan, E.K.L. (2011) Sub-classification of oral squamous cell carcinomas using a novel microRNA-based combinatorial approach. UF College of Dentistry Spring Synergy – Celebration of Science, Gainesville, FL, USA. Oral presentation.

Jung, H.M., Choi, H.J., Kim, H.J., Noh, H.M., and Kim, J.K. (2006) Identification and expression analysis of novel genes that influence the cell immortalization. The 33rd Annual Meeting of the Korean Society of Medical Genetics, Suwon, South Korea. Poster presentation.

Jung, H.M. (2004) Molecular chaperons and their functions. The 43rd National University Student Bio-symposium, Seoul, South Korea. Oral presentation.

Awards & Honors

2013 HHMI Science for Life Graduate Student Award, University of Florida

2013 Silver Medal, Medical Guild Competition, UF College of Medicine

2013 Winner of the Molecular Cell Biology Concentration Medical Guild Competition, UF College of Medicine

2012 Outstanding International Student Award, University of Florida

2012 First Place, Ph.D./Post-doc Basic Science Division Award for Oral Presentation, UF College of Dentistry Spring Synergy – Celebration of Science

2012 Medical Guild Advancement to Candidacy Award, University of Florida College of Medicine

2011 Medical Guild Research Incentive Award, University of Florida College of Medicine

2011 3rd Annual Spring Synergy – Celebration of Science, poster presentation 2nd place, University of Florida College of Dentistry

2009-2013 Alumni Graduate Fellowship, University of Florida College of Medicine

2009 Travel Award, University of Florida College of Medicine

2008 Global Leadership Training Fellowship, CHA University, Seongnam, South Korea

2006 Award for excellent poster presentation, The 33rd Annual Meeting of the Korean Society of Medical Genetics & the 6th Annual Meeting of the East Asian Union of Human Genetics Societies (EAUHGS)

2006 Entitled to the Honors List, Ajou University, Suwon, South Korea

2005 Scholarship C, Ajou University, Suwon, South Korea

2004 Scholarship B, Ajou University, Suwon, South Korea

1999 Presidential Scholarship, Ajou University, Suwon, South Korea